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Trombocytopeni wikipedia

Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.. A normal human platelet count ranges from 150,000 to 450,000 platelets per microliter of blood Platelet-coagulation factor interactions: coagulation facilitation. Platelet activation causes its membrane surface to become negatively charged. One of the signaling pathways turns on scramblase, which moves negatively charged phospholipids from the inner to the outer platelet membrane surface Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel ) because platelets release microparticles that activate thrombin , thereby. Neonatal alloimmune thrombocytopenia (NAITP, NAIT, NATP or NAT) is a disease that affects babies in which the platelet count is decreased because the mother's immune system attacks her fetus' or newborn's platelets. A low platelet count increases the risk of bleeding in the fetus and newborn Background. Thrombocytopenia is defined as platelets of less than 150 x 10 3 /mcL. Symptoms such as bruising and petechiae usually occur at counts at 50 x 10 3 /mcL and between 5-10x 10 3 /mcL there is a high risk of spontaneous bleeding

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Thrombocythemia (also thrombocytosis) is the presence of high platelet (thrombocyte) counts in the blood, and can be either primary (also termed essential thrombocythemia, and caused by a myeloproliferative disease) or secondary (also termed reactive) Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease recently discovered in northeast and central China.SFTS has fatality rates ranging from 12% to as high as 30% in some areas Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. This results in a low platelet count, low red blood cells due to their breakdown, and often kidneys, heart, and brain dysfunction Gestational thrombocytopenia will become evident during the mid-second trimester through the third trimester of pregnancy and it is diagnosed based on exclusion. For example, women with a history of immune thrombocytopenia or thrombocytopenia, prior to pregnancy, will not be diagnosed with gestational thrombocytopenia

Thrombopoietin is a glycoprotein hormone produced by the liver and kidney which regulates the production of platelets.It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets (hematology) An abnormally low number of platelets in the bloo Thrombocytopenia is a blood disease characterized by an abnormally low number of platelets in the bloodstream. The normal amount of platelets is usually between 150,000 and 450,000 cells per microliter of blood. A microliter is an amount equal to one one-millionth of a liter (a liter is almost equal to a quart) Måttlig trombocytopeni ger ofta inga symtom. I takt med graden av trombocytopeni ökar symtomen. Svår trombocytopeni kan ge blödningar i hud s.k petechier (utslag eller blåmärken) och slemhinnor (mun, näsa, tarm, urinvägar och livmoder). I sällsynta fall förekommer blödningar i centrala nervsystemet, leder och muskler. [1

WebMD explains the causes, symptoms, and treatment of thrombocytopenia, a condition that leads you to have low levels of platelets, the cells that help your blood clot A platelet is a cell fragment that circulates in the blood.Platelets are involved in hemostasis through the making of blood clots.A low platelet count (number of platelets in the blood) can cause a person to bleed without their blood clotting (making scabs)

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Heparin-induced thrombocytopenia - Wikipedia

Patients who had platelet counts of less than or equal to 30 x 10 9 /L between cycles and/or who had bleeding related to thrombocytopenia received 0.035 mg/kg PO once per day between courses 14-day cycle for 4 cycles. Reference Immune thrombocytopenic purpura (ITP) is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. People with the disease have too few platelet Thrombocytopenia (thrombocythemia) is a blood disorder characterized by an abnormally low number of of circulating platelets (thrombocytes) in the bloodstream. General description. Platelets play an important role in the process of coagulation (blood clotting) and in the plugging of damaged blood vessels. Persons with decreased platelets bruise. thrombocytosis An increase above normal in the number of PLATELETS (thrombocytes) in the circulating blood. The normal upper limit is about 450,000 per cubic millimetre. Thrombocytosis may be a reactive process or it may be the result of a clonal increase in the number of megakaryocytes in the bone m

Neonatal alloimmune thrombocytopenia - Wikipedia

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